The Murie Ranch was originally homesteaded by Buster Estes. After he found his land unsuitable for the cultivation of crops, he and his Philadelphia socialite wife, Frances Mears, established the successful STS Dude Ranch on the property. When dude ranching declined Estes sold to the Muries in 1945. The Murie Ranch provided a home for renowned wildlife biologists Olaus and Adolph Murie and their families. The brothers both pioneered ground-breaking studies that changed how scientists looked at ecosystems, especially predator-prey relationships. Advocating that the natural processes they studied be allowed to persist without human manipulation put the Muries on the forefront of the conservation movement. Married to sisters– Olaus to Margaret (Mardy) and Adolph to Louise– the close-knit Muries enthusiastically shared their love of the land and their passion for wild places. After retiring from government service, much of which he spent studying elk in Jackson Hole, Olaus accepted co-directorship of the Wilderness Society with the understanding that he could run the society from the ranch. Meetings there led to legislation creating the Wilderness Act and protection of the Artic National Wildlife Refuge. The Murie Ranch grew from a meeting place to an inspirational touchstone for environmentalists.